Volume 3 Issue 4

Welcome to the twelfth edition of Chromatography Today, with the theme for this edition being electrophoretic separations.
As Dave Perrett comments later in his excellent review article: “electrophoresis remains a very important, if somewhat a neglected, analytical technique” It is often viewed very much as a secondary technique, as most current separation solutions can be addressed by other liquid chromatographic options. We should however not forget the role it plays in DNA sequencing and in providing a much needed alternative when tackling high molecular weight or difficult separations.

In This Issue....

• 200 years of Electrophoresis
• Capillary Electrophoresis coupling to Mass Spectrometry (CE-MS), an advanced technique orthogonal toLC-MS for high resolution separation and accurate molecule identification
  3-Dimensional Retention Modelling of Gradient Time, Ternary Solvent-Strength and Temperature of the Reversed-phase Gradient Liquid Chromatography of a Complex Mixture of 22 Basic and Neutral Analytes using DryLab® 2010
• Are Separation Scientists suited to Metabolomics?
• Recent Developments in Type C Stationary Phases:
• Exploiting the Versatility of Silica Hydride Materials Professor Peter J. Schoenmakers: Winner of the 2011 Chromatographic Society Martin Medal
• Separation, size and charge determination of small molecules using CE in combination with UV area imaging
• Chromatography Today talks to Kevin Altria (GSK (Harlow) “CE Expert” and 2006 Chromatographic Society Jubilee Medallist
• Meeting Reports