HPLC, UHPLC
The Use of Temperature for Method Development in LC - Gerd Vanhoenacker , Frank David, Pat Sandra
Sep 09 2010
Author: Gerd Vanhoenacker , Frank David, Pat Sandra on behalf of Unassigned Independent Article
The use of temperature as a tool for method development is gaining interest. In most of the reversed-phase LC methods the selectivity can be altered significantly by changing the temperature. Since temperature is an instrumental parameter it is easier to change than e. g. buffer pH and is more robust. This note demonstrates the potential of temperature variations for controlling the selectivity in LC method development.
Additionally, the features of a silica based and a polymeric stationary phase for elevated temperature LC are highlighted.
Digital Edition
Chromatography Today - Buyers' Guide 2022
October 2023
In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Events
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
ACS National Meeting - Fall 2024
Aug 18 2024 Denver, CO, USA
Sep 04 2024 Chiba, Tokyo, Japan
