HPLC, UHPLC

Early LC-MS Developments in the Laboratory of Professor McLafferty at Cornell University

Author: by APatrick Arpino, on behalf of Laboratoire d'Electrochimie

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A brief account is given on LC-MS research conducted in the laboratory of Professor Fred W. McLafferty at Cornell University during the 70’s. This pioneer work ended into a commercial interface, the Direct Liquid Introduction (DLI) that was later commercialised by mass spectrometer manufacturers, before being superseded by other systems. 

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