Electrophoretic Separations
Seed extract offers pathogen inhibitive qualities
Jul 13 2011
In the study by Vinayak Tripathi, Shailendra Kumar and Satyendra Garg, published by BMC Complementary and Alternative Medicine, Cassia tora, also known as Senna tora, was found to be a proteinaceous protease inhibitor.
Proteases are a key factor in many human, plant and insect pathogens, with inhibitors creating the potential for therapeutic treatment from viral, bacterial, fungal diseases and physiological disorders.
Indeed, Cassia tora has long been used in traditional Indian medicine to effectively treat skin and gastrointestinal disorders.
Using dialysis, size exclusion chromatography and electrophoretic analysis, the scientists discovered that Cassia tora seed extract displayed strong antitryptic, bacterial and fungal protease inhibitory activity.
The extract effectively inhibited residual activity of trypsin, Aspergillus flavus and Bacillus sp. Protease.
"Inhibition of trypsin, bacterial and fungal proteases is indicative of its possible mechanism for varied therapeutic applications," the study stated, adding that it may also be used in crop protection.
Digital Edition
Chromatography Today - Buyers' Guide 2022
October 2023
In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Events
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
ACS National Meeting - Fall 2024
Aug 18 2024 Denver, CO, USA
Sep 04 2024 Chiba, Tokyo, Japan