GC, MDGC
Intelligent use of Relative Response Factors in Gas Chromatography-Flame Ionisation Detection
May 31 2012
Author: Karen Rome and Allyson McIntyre on behalf of AstraZeneca
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Quantitative analysis is required in pharmaceutical R&D to measure the quality of materials used in active pharmaceutical ingredient (API) manufacture, and to monitor the composition of reactions over time. Reagents and matrix typically contain organic carbon, are often volatile and cover a wide range of polarities; therefore Gas Chromatography-Flame Ionisation Detection (GC-FID) is often the appropriate technique.
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