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The analysis of semi-volatile trace contaminants represent a unique challenge to the analytical chemist. Modern techniques of gas chromatography and mass spectrometry have reduced instrumental limits of detection from the nanogram range in the 1970s, using packed chromatography columns...
GC, MDGC, GC-MS
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Static Headspace analysis [1] is the most common sample introduction technique for volatile analysis by Gas Chromatography (GC). It works by analysing the vapour above the sample at equilibrium. However, for detection of trace level analytes, this may not be the most suitable method an...
GC, MDGC, GC-MS
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The use of guard columns within chromatography, both HPLC and GC, is not as widely used as it could be. Many analysts see guard columns as an unnecessary fuss and an extra complication within the whole analytical arrangement. There are many reasons for this, and understanding these reas...
GC, MDGC, GC-MS
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The analysis of flavour compounds in many industries is important for a number of reasons. This can include the differentiation between genuine products and those of lower grade materials produced using different ingredients; for quality control purposes to compare different production...
GC, MDGC, GC-MS
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As available samples become increasingly active, and more complex, you simply cannot afford interferences caused by flow-path activity. A flow path that is not inert can cause peak tailing and signal loss. You can lose critical sample components, leading you to believe they are not pres...
GC, MDGC, GC-MS
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Mixed-mode chromatography is emerging as a powerful tool in separation of various molecules. Mixed-mode is defined as liquid chromatography in which at least two modes of interactions exist simultaneously, both controllable by mobile phase selection. In the last few years, several compa...
GC, MDGC, GC-MS